LINC02874

Across TCGA patient cohorts, LINC02874 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02874-associated genes across cancer lineages are MIR4285, RNU6-621P, and RNU6-1222P. Each is linked with LINC02874 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02874-to-partner and partner-to-LINC02874 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4285 grouped by LINC02874-low versus LINC02874-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02874→partner) and Y-score (partner→LINC02874) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4285 →	+0.743	+4.473	<.001	.005	3	1
UCEC	RNU6-621P →	+0.532	+4.398	.004	.006	3	1
UCEC	RNU6-1222P →	+0.429	+6.736	.006	<.001	3	1
UCEC	MIR608 →	+0.431	+4.621	<.001	.008	3	1
UCEC	MIR7-2 →	+0.498	+4.621	<.001	.008	3	1
UCEC	MIR1251 →	+0.520	+6.470	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MIR4285 by LINC02874 expression — UCEC

Explore this box plot interactively →