LINC02870

Across TCGA patient cohorts, LINC02870 mutation is significantly associated with the RNA expression of many other genes, with 264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02870-associated genes across cancer lineages are ARFGAP2, LAMTOR1, and SEC13. Each is linked with LINC02870 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02870-to-partner and partner-to-LINC02870 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARFGAP2 grouped by LINC02870-low versus LINC02870-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02870→partner) and Y-score (partner→LINC02870) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARFGAP2 →	+0.365	+3.226	.008	.009	3	1
UCEC	LAMTOR1 →	+0.492	+3.595	.001	.001	3	1
UCEC	SEC13 →	+0.533	+3.210	<.001	.009	3	1
UCEC	CCNB2 →	+0.754	+3.201	.009	.009	3	1
UCEC	SNF8 →	+0.581	+3.250	<.001	.008	3	1
UCEC	RNF25 →	+0.456	+3.375	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 264 associations by consensus.

ARFGAP2 by LINC02870 expression — UCEC

Explore this box plot interactively →