LINC02870

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02870 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02870-associated genes across cancer lineages are FoxM1, N-Cadherin, and p27_pT198. Each is linked with LINC02870 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02870-to-partner and partner-to-LINC02870 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by LINC02870-low versus LINC02870-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02870→partner) and Y-score (partner→LINC02870) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFoxM1 →+0.265+2.321.041.03531
UCECN-Cadherin →-0.241-2.321.023.03531
UCECp27_pT198 →+0.147+2.321.006.03531
UCECPCNA →+0.236+2.321.029.03531
UCECAnnexin-1 →+0.608+2.321.021.03531
UCECS6_pS240_S244 →+0.487+2.321.017.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

FoxM1 by LINC02870 expression — UCEC

Box plot of FoxM1 in LINC02870-low vs LINC02870-high samples in UCEC.

Explore this box plot interactively →

Exploration