Across TCGA pan-cancer cohorts, LINC02845 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02845’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02845 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02845 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.
HNSC and UCEC are the cancer types where LINC02845 tumor–normal differential expression is most reproducible.