Across TCGA pan-cancer cohorts, LINC02819 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02819’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC02819 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02819 is over-expressed in tumor, although a few such as CHOL show the opposite, repressed pattern.
LIHC and CHOL are the cancer types where LINC02819 tumor–normal differential expression is most reproducible.