Across TCGA pan-cancer cohorts, LINC02779 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02779’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LINC02779 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02779 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
KICH and LUSC are the cancer types where LINC02779 tumor–normal differential expression is most reproducible.