Across TCGA pan-cancer cohorts, LINC02764 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02764’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02764 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02764 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
HNSC, LUSC, and KICH are the cancer types where LINC02764 tumor–normal differential expression is most reproducible.