Across TCGA pan-cancer cohorts, LINC02759 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02759’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02759 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02759 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.
KIRC and THCA are the cancer types where LINC02759 tumor–normal differential expression is most reproducible.