Across TCGA pan-cancer cohorts, LINC02758 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02758’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC02758 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02758 is over-expressed in tumor, although a few such as STAD and THCA show the opposite, repressed pattern.
STAD, THCA, and ESCA are the cancer types where LINC02758 tumor–normal differential expression is most reproducible.