LINC02754

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02754 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02754-associated genes across cancer lineages are RNU1-17P, MTATP6P21, and LINC02559. Each is linked with LINC02754 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02754-to-partner and partner-to-LINC02754 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by LINC02754-low versus LINC02754-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02754→partner) and Y-score (partner→LINC02754) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU1-17P →+0.459+5.103<.001.00832
UCECMTATP6P21 →+0.296+2.967.003.00732
CESCLINC02559 →+1.376+6.342<.001.00131
CESCRN7SL218P →+0.135+5.812<.001.00331
CESCOR5M14P →+0.072+5.539<.001.00431
CESCAKIRIN2P1 →+0.116+5.669<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

RNU1-17P by LINC02754 expression — CESC

Box plot of RNU1-17P in LINC02754-low vs LINC02754-high samples in CESC.

Explore this box plot interactively →

Exploration