LINC02749

Across TCGA pan-cancer cohorts, LINC02749 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02749’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02749 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02749 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

LUSC, KICH, and COAD are the cancer types where LINC02749 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02749 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.617	<.001	7	view →
KICH	All	IV	−0.730	.002	6	view →
COAD	All	All	+0.430	.001	5	view →
LUAD	All	All	+0.292	.003	3	view →
KIRC	All	II,III,IV	−0.215	.007	3	view →
PRAD	All	All	+0.814	<.001	2	view →
LIHC	Male	II,III,IV	−0.541	.033	1	view →
THCA	All	All	−0.150	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02749–LUSC

Open the LUSC breakdown →