LINC02740

Across TCGA pan-cancer cohorts, LINC02740 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02740’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC02740 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02740 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and KICH are the cancer types where LINC02740 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02740 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.068	<.001	6	view →
BRCA	Female	All	−0.025	.008	3	view →
KICH	Female	All	+0.143	.041	1	view →
KIRP	All	All	+0.099	.040	1	view →
KIRC	Male	All	−0.018	.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02740–THCA

Open the THCA breakdown →