LINC02728

Across TCGA pan-cancer cohorts, LINC02728 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02728’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where LINC02728 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02728 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, BRCA, and STAD are the cancer types where LINC02728 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02728 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.365	<.001	8	view →
BRCA	All	III,IV	−0.625	<.001	6	view →
STAD	Male	II,III,IV	+0.197	.029	4	view →
LUAD	Female	II,III,IV	−0.269	.012	3	view →
LUSC	Male	All	−0.181	.009	2	view →
PRAD	All	All	+0.101	.043	2	view →
CHOL	All	All	+0.222	.027	1	view →
KICH	All	All	−0.155	.006	1	view →
LIHC	All	II,III,IV	+0.064	.042	1	view →
KIRC	Male	II,III,IV	+0.061	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02728–UCEC

Open the UCEC breakdown →