LINC02725

Across TCGA pan-cancer cohorts, LINC02725 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02725’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02725 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02725 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

BRCA, LUAD, and UCEC are the cancer types where LINC02725 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02725 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.345	<.001	4	view →
LUAD	Male	III,IV	+0.363	.008	3	view →
UCEC	All	All	+0.373	.005	2	view →
HNSC	All	All	+0.296	.026	2	view →
LUSC	Female	II,III,IV	−0.134	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02725–BRCA

Open the BRCA breakdown →