Across TCGA pan-cancer cohorts, LINC02722 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC02722’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC02722 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02722 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD are the cancer types where LINC02722 tumor–normal differential expression is most reproducible.