LINC02721

Across TCGA patient cohorts, LINC02721 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,017 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC02721-associated GO terms across cancer lineages are Substrate adhesion-dependent cell spreading, Positive regulation of cytoskeleton organization, and Cellular response to acid chemical. Each is linked with LINC02721 in more than 17 cancer types. Because this analysis shows association rather than direction, both LINC02721-to-partner and partner-to-LINC02721 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substrate adhesion-dependent cell spreading grouped by LINC02721-low versus LINC02721-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02721→partner) and Y-score (partner→LINC02721) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Substrate adhesion-dependent cell spreading →	+0.064	+0.148	<.001	<.001	3	18
STAD	Positive regulation of cytoskeleton organization →	+0.062	+0.182	<.001	<.001	3	16
STAD	Cellular response to acid chemical →	+0.061	+0.207	<.001	<.001	3	16
STAD	Positive regulation of epithelial cell migration →	+0.058	+0.192	<.001	<.001	3	16
STAD	Regulation of stress-activated protein kinase signaling cascade →	+0.060	+0.187	<.001	<.001	3	16
STAD	Regulation of actomyosin structure organization →	+0.055	+0.172	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,017 associations by consensus.

Substrate adhesion-dependent cell spreading by LINC02721 expression — STAD

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