Across TCGA pan-cancer cohorts, LINC02705 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC02705’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02705 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02705 is over-expressed in tumor, although a few such as BRCA and LIHC show the opposite, repressed pattern.
KIRC, BRCA, and LIHC are the cancer types where LINC02705 tumor–normal differential expression is most reproducible.