LINC02691

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02691 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC02691’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC02691 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02691 is over-expressed in tumor, although a few such as KICH and LIHC show the opposite, repressed pattern.

KICH, LIHC, and LUAD are the cancer types where LINC02691 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02691 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHMaleAll−0.876<.00110view →
LIHCMaleII,III,IV−0.447<.0018view →
LUADAllII,III,IV−0.282<.0016view →
COADFemaleIII,IV−0.672.0195view →
LUSCMaleII,III,IV−0.356<.0015view →
KIRCFemaleIII,IV+0.382.0324view →
THCAAllIII,IV−0.063.0044view →
BRCAAllAll−0.057.0184view →
READAllAll−0.629.0073view →
STADAllAll+0.368.0252view →
UCECAllAll−0.236.0082view →
KIRPMaleAll−0.344.0251view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC02691–KICH

Tumor-vs-normal expression box plot for LINC02691 RNA in KICH.

Open the KICH breakdown →

Exploration