LINC02679

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02679 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02679’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02679 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02679 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and BRCA are the cancer types where LINC02679 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02679 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCFemaleII,III,IV−0.652<.0019view →
LUADFemaleII,III,IV−0.524<.0018view →
BRCAFemaleII,III,IV−0.144<.0016view →
KICHFemaleAll−0.116<.0015view →
BLCAAllIII,IV+0.070.0205view →
CHOLFemaleAll+0.260.0262view →
UCECAllAll−0.130.0112view →
STADAllII,III,IV+0.094.0312view →
HNSCFemaleIII,IV+0.092.0192view →
KIRPMaleAll−0.068.0371view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

Exploration