LINC02678

Across TCGA patient cohorts, LINC02678 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,120 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible LINC02678-associated GO terms across cancer lineages are ERBB2 signaling pathway, Regulation of keratinocyte differentiation, and Epidermal cell differentiation. Each is linked with LINC02678 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC02678-to-partner and partner-to-LINC02678 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB2 signaling pathway grouped by LINC02678-low versus LINC02678-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02678→partner) and Y-score (partner→LINC02678) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	ERBB2 signaling pathway →	+0.064	+0.561	<.001	<.001	3	14
STAD	Regulation of keratinocyte differentiation →	+0.040	+0.304	<.001	<.001	3	14
STAD	Epidermal cell differentiation →	+0.041	+0.467	<.001	<.001	3	14
STAD	Keratinocyte differentiation →	+0.043	+0.381	<.001	<.001	3	13
STAD	Positive regulation of epidermis development →	+0.041	+0.461	<.001	<.001	3	13
STAD	Establishment of skin barrier →	+0.050	+0.322	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,120 associations by consensus.

ERBB2 signaling pathway by LINC02678 expression — ESCA

Explore this box plot interactively →