Across TCGA pan-cancer cohorts, LINC02630 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02630’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02630 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02630 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.
BRCA, UCEC, and KIRC are the cancer types where LINC02630 tumor–normal differential expression is most reproducible.