LINC02605

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02605 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02605’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02605 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02605 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, LUSC, and LUAD are the cancer types where LINC02605 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02605 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleIV+0.465<.0019view →
LUSCAllII,III,IV−1.621<.0016view →
LUADAllAll−0.661<.0015view →
STADAllIII,IV+0.698.0054view →
ESCAAllAll+0.881.0122view →
UCECAllAll−0.320.0462view →
PRADAllAll+0.201.0182view →
BRCAAllIII,IV−0.122.0382view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02605–KIRC

Tumor-vs-normal expression box plot for LINC02605 RNA in KIRC.

Open the KIRC breakdown →

Exploration