LINC02599

Across TCGA pan-cancer cohorts, LINC02599 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC02599’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC02599 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02599 is over-expressed in tumor, although a few such as KIRP and BLCA show the opposite, repressed pattern.

KIRP, BLCA, and BRCA are the cancer types where LINC02599 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02599 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.055	<.001	11	view →
BLCA	All	III,IV	−0.127	<.001	8	view →
BRCA	All	II,III,IV	−0.220	<.001	6	view →
UCEC	All	All	−0.182	.002	6	view →
LUSC	Female	II,III,IV	+0.084	.005	4	view →
THCA	All	All	−0.049	<.001	4	view →
COAD	Female	All	−0.036	<.001	4	view →
LUAD	All	II,III,IV	+0.029	.010	4	view →
HNSC	Female	All	+0.115	.015	3	view →
KICH	All	All	−0.062	.007	3	view →
PRAD	All	All	−0.075	<.001	2	view →
READ	Female	All	−0.070	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC02599–KIRP

Open the KIRP breakdown →