LINC02584

Across TCGA pan-cancer cohorts, LINC02584 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC02584’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02584 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02584 is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.

HNSC, COAD, and BLCA are the cancer types where LINC02584 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02584 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.528	<.001	12	view →
COAD	All	All	+0.107	<.001	9	view →
BLCA	All	All	+0.121	.003	7	view →
BRCA	Female	All	−0.394	<.001	6	view →
STAD	All	All	+0.334	.002	6	view →
THCA	Male	All	+0.221	.001	6	view →
KIRC	Male	III,IV	+0.040	.003	5	view →
UCEC	All	All	+0.177	.001	4	view →
LUSC	All	II,III,IV	+0.135	.003	4	view →
LUAD	All	All	+0.128	.007	4	view →
PRAD	All	All	−0.220	.018	2	view →
LIHC	All	All	+0.060	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC02584–HNSC

Open the HNSC breakdown →