Across TCGA pan-cancer cohorts, LINC02583 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02583’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC02583 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02583 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KIRP, HNSC, and BRCA are the cancer types where LINC02583 tumor–normal differential expression is most reproducible.