LINC02552

Across TCGA pan-cancer cohorts, LINC02552 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC02552’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02552 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02552 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and THCA are the cancer types where LINC02552 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02552 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	II,III,IV	−0.214	<.001	7	view →
LUAD	Male	All	−0.177	<.001	7	view →
THCA	Male	III,IV	−0.112	.003	6	view →
KIRC	All	All	+0.026	<.001	5	view →
KICH	Male	IV	−0.053	<.001	3	view →
LIHC	All	All	+0.025	.003	2	view →
HNSC	Male	IV	+0.025	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC02552–LUSC

Open the LUSC breakdown →