LINC02530

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02530 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02530’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC02530 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02530 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, HNSC, and KIRC are the cancer types where LINC02530 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02530 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllII,III,IV−0.150<.00110view →
HNSCAllAll+0.036.0045view →
KIRCAllIV−0.057.0034view →
KIRPAllAll−0.040.0182view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC02530–KICH

Tumor-vs-normal expression box plot for LINC02530 RNA in KICH.

Open the KICH breakdown →

Exploration