Across TCGA pan-cancer cohorts, LINC02501 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC02501’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02501 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02501 is over-expressed in tumor.
LUSC are the cancer types where LINC02501 tumor–normal differential expression is most reproducible.