Across TCGA pan-cancer cohorts, LINC02500 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02500’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC02500 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02500 is over-expressed in tumor, although a few such as STAD and COAD show the opposite, repressed pattern.
STAD and COAD are the cancer types where LINC02500 tumor–normal differential expression is most reproducible.