LINC02499

Across TCGA pan-cancer cohorts, LINC02499 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02499’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02499 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02499 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and KICH are the cancer types where LINC02499 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02499 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−1.167	<.001	12	view →
KIRP	All	III,IV	−1.734	<.001	11	view →
KICH	All	II,III,IV	−0.960	<.001	6	view →
CHOL	Female	All	−4.463	<.001	5	view →
LUSC	All	All	+0.034	.001	5	view →
HNSC	All	III,IV	+0.035	.011	4	view →
LIHC	Female	All	−1.421	<.001	3	view →
PAAD	Male	All	−0.080	.015	2	view →
LUAD	All	II,III,IV	+0.021	.021	2	view →
ESCA	All	All	−0.232	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02499–KIRC

Open the KIRC breakdown →