LINC02495

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02495 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02495’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC02495 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02495 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, LUAD, and KIRC are the cancer types where LINC02495 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02495 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADMaleAll−0.084<.0019view →
LUADFemaleAll+0.323<.0018view →
KIRCAllAll+0.052<.0018view →
BRCAFemaleII,III,IV+0.213<.0016view →
LIHCAllIII,IV+0.074.0096view →
LUSCAllAll+0.086<.0013view →
KICHFemaleAll−0.034.0013view →
READFemaleAll−0.102.0352view →
THCAAllAll−0.042.0142view →
KIRPAllII,III,IV+0.120.0321view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02495–COAD

Tumor-vs-normal expression box plot for LINC02495 RNA in COAD.

Open the COAD breakdown →

Exploration