LINC02461

Across TCGA pan-cancer cohorts, LINC02461 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02461’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC02461 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02461 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

THCA, HNSC, and BRCA are the cancer types where LINC02461 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02461 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	+0.325	<.001	10	view →
HNSC	All	All	+0.103	.002	7	view →
BRCA	Female	All	+0.485	<.001	6	view →
KICH	Male	All	−0.059	.014	4	view →
STAD	All	II,III,IV	+0.254	.035	3	view →
BLCA	Male	All	−0.293	.020	2	view →
ESCA	All	II,III,IV	+0.165	<.001	2	view →
KIRP	All	All	+0.094	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02461–THCA

Open the THCA breakdown →