LINC02453

Across TCGA patient cohorts, LINC02453 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02453-associated genes across cancer lineages are RN7SL147P, VTRNA2-1, and MIR6870. Each is linked with LINC02453 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02453-to-partner and partner-to-LINC02453 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL147P grouped by LINC02453-low versus LINC02453-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02453→partner) and Y-score (partner→LINC02453) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL147P →	+0.312	+4.135	<.001	<.001	3	1
UCEC	VTRNA2-1 →	+0.564	+4.134	.009	.001	3	1
UCEC	MIR6870 →	+0.657	+3.344	<.001	.008	3	1
UCEC	MIR6133 →	+0.456	+3.567	.002	.005	3	1
UCEC	RNA5SP197 →	+0.386	+3.827	.002	.003	3	1
UCEC	RNU6-961P →	+0.213	+5.738	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

RN7SL147P by LINC02453 expression — UCEC

Explore this box plot interactively →