Q-omics provides the consensus-scored LINC02450 profile across patient tissues and cancer cell-line models. LINC02450 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, LINC02450 is differentially expressed in 12, with the highest sampling consensus in HNSC. Additionally, LINC02450 RNA expression shows 10,821 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight ACC, HNSC, and ESCA as cancer lineages where LINC02450 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02450 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02450 survival associations across molecular data types. LINC02450 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02450 RNA expression–survival associations across cancer types. High LINC02450 expression shows unfavorable associations in ACC, KIRC, HNSC, PAAD and LGG, but favorable associations in SKCM. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for LINC02450 RNA expression.
This table summarizes LINC02450 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02450. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02450 shows lower tumor expression in KICH and higher tumor expression in HNSC, BRCA, BLCA, STAD and THCA. The HNSC box plot shows higher LINC02450 RNA expression in tumor versus normal tissue (log2 FC = +0.856, t-test p < 0.001).
This table shows molecular features associated with LINC02450 in patient tissues and cancer cell lines. In patient samples, LINC02450 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
