LINC02435

Across TCGA pan-cancer cohorts, LINC02435 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LINC02435 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher LINC02435 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02435 expression acts as an unfavorable survival marker, although some lineages such as THYM and SKCM show a favorable association.

LGG, GBM, and ACC are the cancer types where LINC02435 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Tertile	All	0.664	0.847	<.001	54	view →
GBM	OS	Tertile	All	0.264	0.489	<.001	30	view →
ACC	DFS	Tertile	II,III,IV	0.107	0.514	.013	18	view →
KIRP	DFS	Quartile	All	0.324	0.605	.011	13	view →
KIRC	DFS	Quartile	II,III,IV	0.332	0.603	.017	10	view →
THYM	OS	Tertile	All	1.000	0.744	.010	9	view →
COAD	DFS	Median	All	0.433	0.661	.026	8	view →
SKCM	DFS	Median	II,III,IV	0.787	0.624	.012	8	view →
UVM	OS	Tertile	All	0.713	0.503	.029	6	view →
UCEC	OS	Median	III,IV	0.663	0.501	.046	4	view →
CHOL	OS	Median	III,IV	0.406	0.961	.040	3	view →
DLBC	DFS	Quartile	All	1.000	0.723	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

LINC02435–LGG (OS)

Open the LGG breakdown →