LINC02427

Across TCGA pan-cancer cohorts, LINC02427 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC02427’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC02427 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02427 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and LIHC are the cancer types where LINC02427 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02427 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	−0.238	<.001	9	view →
THCA	All	All	−0.530	<.001	8	view →
LIHC	All	All	+0.070	<.001	8	view →
KIRC	Male	II,III,IV	−0.727	<.001	7	view →
BRCA	All	All	−0.242	<.001	6	view →
KICH	All	All	−0.893	<.001	5	view →
KIRP	All	III,IV	−0.540	.001	4	view →
UCEC	All	All	−0.429	.004	4	view →
LUSC	Male	All	−0.226	<.001	4	view →
CHOL	All	All	+0.745	.002	2	view →
READ	All	All	−0.557	.028	2	view →
PRAD	All	All	−0.320	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC02427–COAD

Open the COAD breakdown →