LINC02421

Across TCGA pan-cancer cohorts, LINC02421 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LINC02421 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC02421 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC02421 expression acts as an unfavorable survival marker, although some lineages such as PAAD and MESO show a favorable association.

UVM, KIRC, and UCEC are the cancer types where LINC02421 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.510	0.891	<.001	89	view →
KIRC	DFS	Median	All	0.513	0.700	<.001	81	view →
UCEC	OS	Median	IV	0.573	0.895	.002	56	view →
PAAD	OS	Quartile	All	0.664	0.365	.007	47	view →
KICH	DFS	Tertile	III,IV	0.260	0.882	.001	34	view →
KIRP	OS	Quartile	II,III,IV	0.202	0.719	.017	27	view →
MESO	DFS	Median	IV	0.476	0.176	.003	21	view →
SKCM	OS	Median	III,IV	0.471	0.331	.005	20	view →
LIHC	OS	Median	II,III,IV	0.881	0.642	.002	20	view →
READ	OS	Tertile	III,IV	0.659	1.000	.014	20	view →
STAD	OS	Tertile	IV	0.652	0.202	.024	16	view →
LUAD	DFS	Tertile	IV	0.502	1.000	.019	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

LINC02421–UVM (DFS)

Open the UVM breakdown →