LINC02378

Across TCGA patient cohorts, LINC02378 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,502 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC02378-associated GO terms across cancer lineages are Regulation of double-strand break repair, Regulation of microtubule cytoskeleton organization, and Regulation of double-strand break repair via homologous recombination. Each is linked with LINC02378 in more than 11 cancer types. Because this analysis shows association rather than direction, both LINC02378-to-partner and partner-to-LINC02378 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by LINC02378-low versus LINC02378-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02378→partner) and Y-score (partner→LINC02378) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair →	+0.070	+0.158	<.001	<.001	3	12
STAD	Regulation of microtubule cytoskeleton organization →	+0.066	+0.148	<.001	<.001	3	12
STAD	Regulation of double-strand break repair via homologous recombination →	+0.069	+0.147	<.001	<.001	3	12
STAD	DNA-templated transcription termination →	+0.064	+0.149	<.001	<.001	3	11
STAD	Mitochondrial gene expression →	+0.085	+0.180	<.001	<.001	3	11
ESCA	Positive regulation of cell cycle phase transition →	+0.064	+0.239	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,502 associations by consensus.

Regulation of double-strand break repair by LINC02378 expression — STAD

Explore this box plot interactively →