LINC02356

Across TCGA pan-cancer cohorts, LINC02356 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02356’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02356 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02356 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and BRCA are the cancer types where LINC02356 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02356 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−1.207	<.001	8	view →
LUAD	Female	II,III,IV	−0.790	<.001	8	view →
BRCA	Female	II,III,IV	−0.693	<.001	8	view →
HNSC	All	All	−0.315	<.001	8	view →
KICH	All	All	−0.551	<.001	7	view →
KIRC	All	All	+0.168	.002	5	view →
UCEC	All	All	−0.556	.012	2	view →
LIHC	All	III,IV	+0.493	.021	2	view →
THCA	Male	IV	−0.419	.025	2	view →
BLCA	Female	IV	−0.483	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02356–LUSC

Open the LUSC breakdown →