LINC02354

Across TCGA pan-cancer cohorts, LINC02354 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC02354 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher LINC02354 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC02354 expression acts as an unfavorable survival marker, although some lineages such as MESO and BRCA show a favorable association.

MESO, KIRP, and BRCA are the cancer types where LINC02354 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.712	0.308	.003	76	view →
KIRP	DFS	Median	All	0.791	0.908	<.001	67	view →
BRCA	OS	Median	II,III,IV	0.942	0.883	<.001	57	view →
HNSC	OS	Quartile	All	0.510	0.281	.002	53	view →
THCA	DFS	Tertile	All	0.909	0.961	.004	45	view →
KIRC	DFS	Tertile	II,III,IV	0.681	0.837	.010	41	view →
READ	OS	Tertile	All	1.000	0.565	.007	32	view →
UCEC	DFS	Median	All	0.449	0.725	.017	28	view →
CHOL	DFS	Median	All	0.661	0.263	.016	21	view →
COAD	OS	Tertile	IV	0.844	0.308	.017	18	view →
DLBC	DFS	Median	II,III,IV	1.000	0.331	.006	11	view →
THYM	OS	Tertile	II,III,IV	1.000	0.668	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC02354–MESO (OS)

Open the MESO breakdown →