LINC02351

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02351 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC02351 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher LINC02351 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02351 expression acts as an unfavorable survival marker, although some lineages such as HNSC and DLBC show a favorable association.

LIHC, HNSC, and THCA are the cancer types where LINC02351 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.6050.813<.00199view →
HNSCDFSQuartileIII,IV0.7760.619.00347view →
THCAOSTertileAll0.9730.996.00139view →
BRCADFSTertileAll0.5701.000.03336view →
DLBCDFSTertileAll0.9380.314.00429view →
THYMOSMedianII,III,IV0.6981.000.00124view →
UCECOSQuartileIII,IV0.7090.841.02120view →
READDFSQuartileIII,IV0.3960.814.00515view →
KIRPOSTertileAll0.4880.827.01514view →
KICHDFSTertileIII,IV0.0430.897.0459view →
LUSCDFSTertileAll0.3140.458.0209view →
MESOOSQuartileIV0.9350.437.0168view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC02351–LIHC (OS)

Kaplan–Meier survival curve for LINC02351 RNA-high vs -low samples in LIHC.

Open the LIHC breakdown →

Exploration