LINC02348

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02348 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC02348’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02348 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02348 is over-expressed in tumor, although a few such as CHOL show the opposite, repressed pattern.

KIRC, BRCA, and LUSC are the cancer types where LINC02348 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02348 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCFemaleAll+4.114<.00112view →
BRCAAllIII,IV+0.577<.0016view →
LUSCAllAll+0.264<.0016view →
KIRPAllII,III,IV+0.443.0164view →
COADFemaleAll+0.095.0104view →
CHOLAllAll−1.134.0012view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC02348–KIRC

Tumor-vs-normal expression box plot for LINC02348 RNA in KIRC.

Open the KIRC breakdown →

Exploration