Across TCGA pan-cancer cohorts, LINC02324 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02324’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC02324 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02324 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
LUAD, BRCA, and KIRP are the cancer types where LINC02324 tumor–normal differential expression is most reproducible.