LINC02315

Across TCGA pan-cancer cohorts, LINC02315 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02315’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02315 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02315 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LUSC, HNSC, and BLCA are the cancer types where LINC02315 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02315 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	+2.031	<.001	7	view →
HNSC	Male	All	+0.924	.003	7	view →
BLCA	All	All	+1.406	.003	6	view →
THCA	Male	IV	−0.603	<.001	5	view →
KIRC	Female	II,III,IV	−0.357	.001	5	view →
LIHC	All	All	+0.434	.002	4	view →
KIRP	Female	All	−0.549	.011	3	view →
KICH	All	IV	−0.290	.007	3	view →
LUAD	All	II,III,IV	+0.657	.024	2	view →
UCEC	All	All	−0.336	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02315–LUSC

Open the LUSC breakdown →