LINC02314

Across TCGA pan-cancer cohorts, LINC02314 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated LINC02314 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC02314 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02314 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CHOL show a favorable association.

HNSC, BRCA, and KIRC are the cancer types where LINC02314 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	IV	0.130	0.659	<.001	81	view →
BRCA	OS	Tertile	All	0.820	0.554	.004	66	view →
KIRC	OS	Tertile	All	0.489	0.656	.002	42	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.007	36	view →
CESC	OS	Tertile	III,IV	0.280	0.676	.018	36	view →
LGG	DFS	Tertile	All	0.313	0.763	<.001	27	view →
LUSC	DFS	Tertile	All	0.617	0.758	.010	24	view →
LUAD	OS	Tertile	II,III,IV	0.522	0.721	.015	15	view →
CHOL	DFS	Tertile	II,III,IV	1.000	0.147	.041	9	view →
THYM	OS	Tertile	All	0.734	0.971	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

LINC02314–HNSC (OS)

Open the HNSC breakdown →