LINC02298

Across TCGA pan-cancer cohorts, LINC02298 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC02298’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02298 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02298 is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.

KIRC, HNSC, and THCA are the cancer types where LINC02298 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02298 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.855	<.001	11	view →
HNSC	Male	All	+0.901	<.001	10	view →
THCA	Male	All	+0.632	<.001	7	view →
LIHC	All	II,III,IV	+0.951	<.001	6	view →
BLCA	All	III,IV	+0.796	.033	6	view →
CHOL	Female	All	+2.936	<.001	5	view →
COAD	Male	All	+0.614	.006	4	view →
BRCA	All	II,III,IV	−0.403	<.001	4	view →
KIRP	All	II,III,IV	+0.978	.009	3	view →
PAAD	All	All	+0.897	.013	2	view →
PRAD	All	All	−0.782	<.001	2	view →
READ	Female	All	+0.870	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC02298–KIRC

Open the KIRC breakdown →