long intergenic non-protein coding RNA 2289Genealiases: []
Q-omics provides the consensus-scored LINC02289 profile across patient tissues and cancer cell-line models. LINC02289 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC02289 is differentially expressed in 13, with the highest sampling consensus in KIRP. Additionally, LINC02289 RNA expression shows 14,369 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KIRC, KIRP, and ACC as cancer lineages where LINC02289 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02289 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02289 survival associations across molecular data types. LINC02289 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02289 RNA expression–survival associations across cancer types. High LINC02289 expression shows unfavorable associations in KIRP, CESC and LAML, but favorable associations in KIRC, LIHC and MESO. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC02289 RNA expression.
This table summarizes LINC02289 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02289. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02289 shows lower tumor expression in KIRP, LUAD, LUSC, BRCA and KICH and higher tumor expression in KIRC. The KIRP box plot shows higher LINC02289 RNA expression in normal versus tumor tissue (log2 FC = −0.561, t-test p < 0.001).
This table shows molecular features associated with LINC02289 in patient tissues and cancer cell lines. In patient samples, LINC02289 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
