LINC02287

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02287 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02287’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LINC02287 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02287 is over-expressed in tumor, although a few such as BLCA and ESCA show the opposite, repressed pattern.

BLCA, HNSC, and ESCA are the cancer types where LINC02287 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02287 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BLCAAllIII,IV−0.217.0038view →
HNSCFemaleII,III,IV+0.023.0156view →
ESCAAllAll−0.250.0192view →
READAllAll−0.188.0042view →
COADFemaleII,III,IV−0.109<.0012view →
KICHAllAll−0.066.0191view →
KIRCAllAll−0.025.0361view →
THCAMaleAll−0.013.0351view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02287–BLCA

Tumor-vs-normal expression box plot for LINC02287 RNA in BLCA.

Open the BLCA breakdown →

Exploration