Across TCGA pan-cancer cohorts, LINC02279 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02279’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02279 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02279 is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.
BRCA, HNSC, and KICH are the cancer types where LINC02279 tumor–normal differential expression is most reproducible.