LINC02265

Across TCGA pan-cancer cohorts, LINC02265 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC02265’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02265 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02265 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and THCA are the cancer types where LINC02265 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02265 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	II,III,IV	−0.970	<.001	8	view →
LUAD	Female	All	−0.926	<.001	8	view →
THCA	Female	All	−0.250	<.001	4	view →
COAD	Female	II,III,IV	−0.038	.011	4	view →
UCEC	All	All	−0.739	.032	2	view →
HNSC	Male	III,IV	+0.151	.017	2	view →
PAAD	Male	All	+0.130	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC02265–LUSC

Open the LUSC breakdown →